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Alternatively, it may be desirable in SCD to raise ATP levels (needed for basal and inducible ATP export, and for numerous intracellular homeostatic actions) without elevating DPG levels, or even while reducing DPG content

Oral glutathione is generally well-tolerated, with mild gastrointestinal side effects including flatulence and loose stools reported in some cases, which typically resolve spontaneously, and is considered possibly safe when used in doses up to 500 mg daily for up to 2 months

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Knockdown of FBI-1 induced the ferroptosis of PC-3 cells (Figure 1B and C)

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